Idiopathic hyposmia as a preclinical sign of Parkinson's disease

Idiopathic hyposmia as a preclinical sign of Parkinson's disease.

Olfactory dysfunction is an early and common symptom in Parkinson's disease (PD). In an effort to determine whether otherwise unexplained (idiopathic) olfactory dysfunction is associated with an increased risk of developing PD, we designed a prospective study in a cohort of 361 asymptomatic relatives (parents, siblings, or children) of PD patients. A combination of olfactory detection, identifi...

hair loss as a sign of kawasaki disease

kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

Idiopathic intracranial hypertension as a presenting sign of adrenal insufficiency

Idiopathic intracranial hypertension is a diagnosis of exclusion defined by elevated intracranial pressure without mass lesions or hydrocephalus. Causes of idiopathic intracranial hypertension include obesity, vitamin derangements, antibiotics, corticosteroids, and autoimmune disorders. Cushing's disease and Addison's disease have been associated with idiopathic intracranial hypertension. Secon...

Neural Basis of Hyposmia in Alzheimer’s Disease

Idiopathic atrophic glossitis as the only clinical sign for celiac disease diagnosis: a case report

INTRODUCTION The aim of this case report is to show how an oral condition, such as atrophic glossitis, can be the only clinical sign that allows an early diagnosis of celiac disease. CASE PRESENTATION Atrophic glossitis was detected by a dentist during a first routine examination of the oral cavity of a 17-year-old Sardinian young woman and then differential diagnosis was carried out to ident...